The second game, which will see Orioles third baseman Manny Machado activated after serving a five-game suspension, will start at its regularly scheduled 7:15 p.m. time. The Red Sox will start right-hander John Lackey for Game 2.
The Orioles' official starters have yet to be announced.
Brittany Ghiroli is a reporter for MLB.com. Read her blog, Britt's Bird Watch, and follow her on Facebook and Twitter @britt_ghiroli. This story was not subject to the approval of Major League Baseball or its clubs.