Following that first series, which runs from April 2-4, the Orioles will return to Camden Yards for a three-game set against the Minnesota Twins. The famed ballpark, which will be in its 21st season, will host an eight-game homestand (the Rays, Angels and Blue Jays) starting on April 16, with road series against Boston and New York before that.
New to the American League is the Astros, and the Orioles will travel to Minute Maid Park for a series from June 4-6. The O's will host Houston at Camden Yards from July 30-Aug. 1. That three-game set ensures the O's will be in Baltimore during the non-waiver Trade Deadline on July 31.
For Interleague Play, the O's will host the San Diego Padres on May 14-15. The Beltway Series against the Washington Nationals will be a home-and-home series. Baltimore will travel to Washington for a brief two-game set from May 27-28, and then the O's will host the Nationals for a pair after that on May 29-30.
Baltimore will close out the first half with a seven-game homestand: four games against the Texas Rangers and three against the Toronto Blue Jays. The O's will face the Rangers again to open the second half after the break for a weekend three-game series in Arlington that begins on July 19.
One of the more interesting road trips next season is a three-city Interleague trip out west that starts with two games in San Diego's Petco Park on Aug. 6. Following an off-day, the O's will play three games apiece in San Francisco and Arizona, the organization that O's manager Buck Showalter helped get off the ground.
Following that trip, Baltimore will return home to the East Coast for Interleague Play, as it plays host to the Colorado Rockies for a three-game series starting Aug. 16. The final month of the season features the typical slew of divisional games.
The Orioles finish the regular season with a three-game home series against the Boston Red Sox for the second time in three seasons. The matchup, which begins Sept. 29, will be a rematch of the fateful final days of 2011, when the O's bested the Red Sox to help Tampa Bay make the postseason and send Boston to a historic collapse.
Brittany Ghiroli is a reporter for MLB.com. Read her blog, Britt's Bird Watch, and follow her on Twitter @britt_ghiroli. This story was not subject to the approval of Major League Baseball or its clubs.