The news came on a conference call announcing the hiring of new amateur scouting director Gary Rajsich, and executive vice president of baseball operations Dan Duquette indicated that more changes are on the horizon.
"We will make other changes to the staff to make sure we are strong, not just in amateur scouting, but at all levels," said Duquette, who added that the Orioles aren't likely to replace MacPhail's position but will have "appropriate" staffing at all levels of the organization.
The nephew of former president of baseball operations Andy MacPhail, Lee MacPhail spent 3 1/2 years as an area scout for the Minnesota Twins, and he was a professional scout in 2007 before the Orioles hired him that October.
Brittany Ghiroli is a reporter for MLB.com. Read her blog, Britt's Bird Watch, and follow her on Twitter @britt_ghiroli. This story was not subject to the approval of Major League Baseball or its clubs.