Manager Buck Showalter said Guerrero told him his wrist had been improving, but he wanted to take another day to see how it feels. The Orioles may call for an X-ray after consulting with team physician William Goldliner.
Third baseman Mark Reynolds, who was also forced to leave the game Sunday after being hit in the right hand by Weiland, started Thursday's series opener with the Indians.
The initial X-rays, taken on Sunday, of both Reynolds and Guerrero came back negative.
Guerrero hit .279 with seven home runs and 31 RBIs in the first half of the season. Four of those homers came in April, and the former Silver Slugger winner has three RBIs in his past 10 games.